Over one million people are estimated to currently have glaucoma in the UK, a figure projected to reach more than 1.6 million by 2060, according to a study led by Moorfields and UCL researchers.
The new figures, published in the British Journal of Ophthalmology and commissioned by Glaucoma UK, are nearly 50% higher than previous estimates of glaucoma prevalence. The researchers say there could be more than half a million people with undiagnosed glaucoma - a common eye condition in which the optic nerve, which connects the eye to the brain, becomes damaged - in the UK.
The researchers project that glaucoma rates will increase more rapidly than total population growth, largely due to the ageing population, putting increasing pressure on health services. They are calling for an expansion of eye health services and encouraging people to get their eyes checked regularly.
The study’s lead author Professor Paul Foster, a consultant ophthalmic surgeon at Moorfields Eye Hospital and researcher at UCL Institute of Ophthalmology, said: “Glaucoma is a common cause of blindness, but it isn’t symptomatic until its later stages, so regular tests are important for early diagnosis. Previous studies have estimated that half of glaucoma cases are undiagnosed, and this is even higher among some ethnic minority groups who are more likely to experience delays in diagnosis.
“Late diagnosis comes with a higher risk of sight loss and higher costs of care; over 40% of glaucoma patients in the UK experience vision loss that could have been prevented with earlier diagnosis and treatment such as eye drops or surgery.”
Glaucoma is the leading cause of irreversible blindness globally. The most important risk factors are high pressure in the eye and older age. Glaucoma often has no symptoms until a considerable amount of vision has been permanently lost.
To develop their new estimates of glaucoma prevalence, the researchers used UK-wide data on age, sex and ethnicity for people aged 40 and over (as glaucoma is very rare before this age), and grouped them by five-year age bands, sex, and four broad ethnic categories: European, African, Asian, and mixed/other.
They estimated how many people in each group are likely to have glaucoma based on the best available evidence of prevalence within particular demographic groups internationally. This was based on age- and sex-specific estimates for glaucoma prevalence for people with European ancestry sourced from the European Eye Epidemiology Consortium. For non-European ethnic groups, the researchers used relative risk estimates from other studies and applied them to the European baseline.
The researchers estimate that 1.1 million people in the UK currently have glaucoma, or 3% of the population over 40. This percentage is believed to be higher, at 4%, among those of African descent. Among people over 85, 11% are estimated to have glaucoma.
Previous estimates suggested that around 700,000 people were living with glaucoma in the UK, but the researchers say this was underestimating how many people were undiagnosed and did not fully account for recent demographic shifts.
Although non-European groups represent only 6% of the UK population aged 65 and older, the researchers estimate that they account for 8% of current glaucoma cases. People of African origin are known to face a higher risk of glaucoma, partly due to genetic factors.
To estimate future disease burden, the researchers used population projections from the UK’s Office for National Statistics. The researchers predict a 60% increase in cases by 2060, to a total of 1.61 million, despite the population of over-40s expected to increase by only 28%. This difference is largely due to population growth of people over 75.
Professor Foster said: “Our findings show that there will be a large increase in glaucoma cases in the UK, so there’s a growing need to expand eye health services to meet this demand, including specialist care and diagnostic capacity.
“Awareness campaigns encouraging people to get their eyes checked are also needed as part of targeted early detection strategies, particularly to address late diagnosis in underserved, hard to reach populations.
“For people in midlife onwards, it’s important to get your eyes checked annually by your optician, to detect changes that haven’t yet caused any symptoms.”
Joanne Creighton, CEO of Glaucoma UK, said: “This new study reveals a reality where over one million adults aged 40 and above are currently living with glaucoma – many of them without knowing, and potentially losing sight which they will never be able to recover.
“This landmark study also predicts a 60% increase in glaucoma cases by 2060, rising from just over one million to 1.61 million. This is a demographic timebomb, and we need serious planning and action now to prepare to diagnose, treat, and support these future patients. These findings highlight why routine eye tests are more important than ever before.”
View the paper at: Current burden and future projections of glaucoma in the United Kingdom | British Journal of Ophthalmology
