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Targeting global threats of sepsis and AMR

Sepsis improvement programmes have received criticism, in recent years, with some claiming that they have ‘resulted in increased hospital antimicrobial consumption’. But should we be targeting sepsis management as ‘the low hanging fruit’ or should we be looking elsewhere for solutions – including better integration of diagnostics? Louise Frampton reports.

Earlier this year, an analysis of 204 countries and territories, revealed that AMR is now a leading cause of death worldwide, higher than HIV/AIDS or malaria. It showed that more than 1.2 million people – and potentially millions more – died in 2019 as a direct result of antibiotic-resistant bacterial infections.

Published in The Lancet,1 the report highlighted an urgent need to scale up action to combat AMR, and outlined immediate actions for policymakers to help save lives and protect health systems. These included optimising the use of existing antibiotics, taking greater action to monitor and control infections, and providing more funding to develop new antibiotics and treatments.

Of the 23 pathogens studied, drug resistance in six alone (E. coli, S. aureus, K. pneumoniae, S. pneumoniae, A. baumannii, and P. aeruginosa) led directly to 929,000 deaths and was associated with 3.57 million. One pathogen-drug combination – methicillin-resistant S.aureus, or MRSA – directly caused more than 100,000 deaths in 2019, while six more each caused between 50,000 and 100,000 deaths.

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Upcoming Events

Central Sterilising Club - Annual Scientific Meeting 2024

Crowne Plaza at Gerrard’s Cross
15th April 2024 – 16th April 2024

DECON UK 2024

National Conference Centre, Birmingham
17th April 2024

Infection Prevention & Control

National Conference Centre, Birmingham
23rd - 24th April 2024

Theatres & Decontamination Conference 2024

Coventry Building Society Arena
16th May 2024

The AfPP Roadshow - Birmingham

Millennium Point, Birmingham
18th May 2024

The AfPP Roadshow - Exeter

University of Exeter
22nd June 2024

Access the latest issue of Clinical Services Journal on your mobile device together with an archive of back issues.

Download the FREE Clinical Services Journal app from your device's App store

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