The website of the Clinical Services Journal

Clinical trial network could boost search for new antibiotics

A network to run clinical trials could make finding new antibiotics cheaper and more efficient, according to a report from the Wellcome Trust.

There are not enough new antibiotics being created to combat the growing problem of drug-resistant infections, but research to develop new antibiotics is challenging. For example, between 50 and 300 hospitals must be found and enrolled into every trial.

The report outlines the benefits of creating a clinical trials network:

  •  Trials would be able to quickly plug into a network of hospitals rather than have to find their own sites.
  •  Standardising research protocols across the network would mean different trials could share the same control groups of patients.

Initial estimates also suggest a network could result in savings of up to 23% on clinical trial running costs and between 40% and 60% of the total cost of trials if a master trial protocol is used and multiple trials share a single control group. 

Wellcome's director Jeremy Farrar said: "We’re entering a post-antibiotic era. Hundreds of thousands of people die every year from drug-resistant infections, and numbers are increasing at an alarming rate. New antibiotics are urgently needed, but so far their development has been inefficient and costly. 

“This report highlights innovative models for clinical trials to reduce these barriers, and offers imaginative ways to implement a quicker, less costly and practical system for assessing new antibiotics in a way that would provide the critical robust evidence on safety and efficacy.” 

Chief Medical Officer, Professor Dame Sally Davies, said: “We must focus on developing a new generation of antibiotics. This report highlights how making clinical trials quicker, cheaper and easier will help develop the drugs the world needs. I hope that researchers, industry and regulators will build on Wellcome’s research to help make the antibiotic pipeline as effective as possible.” To download the report, visit: https://wellcome.ac.uk/sites/default/files/ clinical-trial-networks-for-antibioticdevelopment-wellcome-oct16.pdf

 

Upcoming Events

Central Sterilising Club - Annual Scientific Meeting 2024

Crowne Plaza at Gerrard’s Cross
15th April 2024 – 16th April 2024

DECON UK 2024

National Conference Centre, Birmingham
17th April 2024

Infection Prevention & Control

National Conference Centre, Birmingham
23rd - 24th April 2024

Theatres & Decontamination Conference 2024

Coventry Building Society Arena
16th May 2024

The AfPP Roadshow - Birmingham

Millennium Point, Birmingham
18th May 2024

The AfPP Roadshow - Exeter

University of Exeter
22nd June 2024

Access the latest issue of Clinical Services Journal on your mobile device together with an archive of back issues.

Download the FREE Clinical Services Journal app from your device's App store

Upcoming Events

Central Sterilising Club - Annual Scientific Meeting 2024

Crowne Plaza at Gerrard’s Cross
15th April 2024 – 16th April 2024

DECON UK 2024

National Conference Centre, Birmingham
17th April 2024

Infection Prevention & Control

National Conference Centre, Birmingham
23rd - 24th April 2024

Theatres & Decontamination Conference 2024

Coventry Building Society Arena
16th May 2024

The AfPP Roadshow - Birmingham

Millennium Point, Birmingham
18th May 2024

The AfPP Roadshow - Exeter

University of Exeter
22nd June 2024

Access the latest issue of Clinical Services Journal on your mobile device together with an archive of back issues.

Download the FREE Clinical Services Journal app from your device's App store

Step Communications Ltd, Step House, North Farm Road, Tunbridge Wells, Kent TN2 3DR
Tel: 01892 779999
www.step-communications.com
© 2024 Step Communications Ltd. Registered in England. Registration Number 3893025